MOZART project
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Modelling Zoonotic & Arthropod-borne pathogens

MoZArt is a research project on the epidemiology of vector-borne and zoonotic pathogens (i.e., transmitted from animals to humans by infected arthropods vectors, such as ticks and mosquitoes).
As model studies, we are primarily interested in Lyme borreliosis  (LB) and tick-borne encephalitis (TBE), tick-borne zoonoses both transmitted by the same hard tick Ixodes ricinus.  By combining modelling approaches together with laboratory, field and satellite imagery data, our interdisciplinary "One Health" approach aims to understand how ticks, animals, humans and the environment  interact to shape diseases' pattern.

<< News >>

April - Mai 2025 -   We are very proud to publish two papers one month apart, also showing the range of expertise our team spans !
First, considering seasonality of tick questing, we revisited mapping work on  the spatial expansion risk of H. longicornis  tick in North America and Europe , using ecological niche modelling approach, check   here
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Here, we explored how Antibioclic, a Computerised decision support system, can help in better understanding Lyme borreliosis epidemiology.  
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January 2025 -  We released a new preprint, looking at Borrelia and Tick-borne encephalitis serology in roe deer in France
November 2024 -  Our team is heading to  Rennes , to the ​annual modelling days of ANRS, communicating on our research on  modelling the eco-epidemiology of Ixodes-transmitted pathogens
October 2024 -  Ilona presented her PhD work  on spatial modelling to improve Lyme disease estimation incdience at the national symposium ArboFrance
June 2024 -  Our model,   looking at the  population dynamics of Ixodes ricinus is available as a pre-print
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​May 2024 -
Both   
Armelle  Poisson and Laure   Mathews-Martin papers'   are    out, exploring tick-borne zoonoses from the animal perspective
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February 2024 -    Ingrid Wongoue  recently joined us to  estimate contact rates  at the tick-human interface and factors associated
October 2023 -    Ilona Suhanda joined our team; her  PhD will focus on joint spatial modelling of Lyme and TBE
September 2023 - We are delighted to welcome Younjung Kim  in our team as a post-doctoral research fellow in mathematical modelling
September 2023 -   Laure    will present  her poster  "Seroprevalence and factors associated with the exposure of cattle to the tick-borne encephalitis virus (TBEV) in the Northeastern part of France" at the    10th European Meeting on Viral Zoonosis, Sept 23-26 2023, St-Raphaël – France
August 2023 -   📣 New pre-print !!!   📣
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We reviewed the literature to investigate how tick-borne flaviviruses and borrelia infections have been studied in wildlife  and discuss their relevance in providing epidemiological information useful to understand pathogens' transmission
​To read it, click here 
July 2023 -   Armelle   presented her internship work on    sero-epidemiology in wildlife hosts at the  national conference "Rencontres du GdR phylodynamique" 
March 2023 -   Data collection is ongoing
From  human exposure to tick bites to infection data in potential animal reservoirs, we are  setting  up and gathering the most up-to-date datasets to get further insights on both Lyme and TBE 
March 2023 -  📣 New paper out !!!   📣
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We looked at the spatial and seasonal determinants of  Lyme borreliosis in France by analysing surveillance data with Bayesian statistics
Fu W, Bonnet C, Septfons A, Figoni J, Durand J, Frey-Klett P, Rustand D, Jaulhac B, Métras R. Spatial and seasonal determinants of Lyme borreliosis incidence in France, 2016 to 2021. Euro Surveill. 2023 Apr;28(14). doi: 10.2807/1560-7917.ES.2023.28.14.2200581. PMID: 37022210.

January 2023 - Our four-years  project has started !
MoZArt is a four-years ANRJCJC project (2023-2026, ANR-22-CE35-0003) funded by 
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Project PI:     Raphaëlle Métras
Pierre Louis Institute of Epidemiology and Public Health (IPLESP, UMRS-1136),   Sorbonne Université , Inserm,   27 rue Chaligny, 75012 Paris, France
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